While stuck at a wedding in Palm Springs, Nyles (Andy Samberg) meets Sarah (Cristin Milioti), the maid of honor and family black sheep. After he rescues her from a disastrous toast, Sarah becomes drawn to Nyles and his offbeat nihilism. But when their impromptu tryst is thwarted by a surreal interruption, Sarah must join Nyles in embracing the idea that nothing really matters, and they begin wreaking spirited havoc on the wedding celebration.
Andy Samberg admitted multiple endings were written and even shot. They held private friends and family screenings of the different versions to get opinions on which ending worked. Samberg jokes, “Alright, it might not be perfect but everyone liked it!”